Incomplete glimpses of the philosophy of Charles Peirce (1839-1914) can frequently be found in studies about Semiotics and Information Science. Therefore, we sought to discover the theoretical and applied interrelationships between knowledge and information organization and Peirce's Semiotics and Philosophy. The aim was to discover and evaluate the contributions of Peirce's Semiotics and Philosophy to the knowledge and information organization field. The method of this study was bibliographical research. The main results were: indexing process semiotic model, semiotic knowledge organization, interaction between documentary semiotics and documentary languages, kinds of inference to the indexing process, as well as the collaboration of Peirce's pragmatism to terminology theory. Finally, we listed issues for future research.