It outlines a preliminary examination of how the relationship between manifestations of the disease, scientific discoveries and technological production for the main outbreaks of the coronavirus, between 2000 and 2020, was established in order to consolidate knowledge that can corroborate for an expanded understanding of the pandemic. It adopts as basic subjects for the bibliographic review the interlocution between science, technology and innovation as well as the relevant aspects for understanding the trajectory of the coronavirus family: main outbreaks (2002, 2012 and 2019) and scientific discoveries. It presents a timeline of outbreaks caused by the virus in order to compose a picture with the trajectory of the main discoveries made by the scientific community that studies the theme, supported by the studies by Weiss (2020). Through a previous study carried out in Questel Orbit, it measures the patent applications per existing family, highlighting the period of publication, main filing countries, clusters and technological domains and historical series by the International Patent Classification (CIP). It evaluates the exposed trajectories and concludes that a greater alignment between science, technology and innovation is necessary to promote quick and forceful responses to the diseases generated by the coronavirus