Health information available on websites may not have the expected effects on the communities of interest due to inadequacies in their information design project. The aim of this paper is to analyze three of these websites of Brazilian public institutions with information about zika virus and microcephaly, from the bibliographic analysis, under the perspective of information design. The results of the analyzes are presented and recommendations are made for new materials available on web 2.0, focused on the topic of microcephaly by zika virus. Reflection is necessary in view of the sociopolitical and cultural reality of Brazilian contemporaneity.